Brand Name

Not specified

Dosage Form

Oral tablets

Strength

Not specified

Manufacturer

Not specified

Conditions Studied

  • Medicines were shipped from an established supplier in the Netherlands to the Nile Province Essential Drug Project in Sudan in May 1989
  • Containers arrived in July 1989 in Port Sudan and were not climate-controlled, with temperatures frequently reaching above 50 degrees Celsius in the first three months of storage
  • Medicines were distributed in February 1990, and samples were taken in August 1990 and compared to batch samples kept by the supplier

Temperature (degrees Celsius)

  • Frequently above 50
  • No climate control was maintained

Humidity (%)

Not specified

Countries Studied In

Sudan

Definition of Stability

Not specified. Potency was compared between batches stored by the supplier and batches samples in-field.

Conclusions and Length of Stability

  • Potency:
    • Supplier: 98.0%
    • In-field: 98.2%
  • Author's conclusions: Acetylsalicylic acid did not show signs of stability under the conditions studied

Reference

Hogerzeil HV, De Goeje MJ, Abu-Reid, IO. Stability of essential drugs in Sudan. Lancet 1991; 338: 754-755.

MeSH entry terms
  • Acetylsalicylic Acid
  • Acid, Acetylsalicylic
  • 2-(Acetyloxy)benzoic Acid
  • Acylpyrin
  • Aloxiprimum
  • Colfarit
  • Dispril
  • Easprin
  • Ecotrin
  • Endosprin
  • Magnecyl
  • Micristin
  • Polopirin
  • Polopiryna
  • Solprin
  • Solupsan
  • Zorprin
  • Acetysal
MeSH reference: http://www.ncbi.nlm.nih.gov/mesh/68001241

Written by: Alex Evans, PharmD
Reviewed by:
Last updated: May 5, 2013