Brand Name

Not specified
Dosage Form


Not specified
Strength

Not specified

Manufacturer


Not specified
Conditions Studied
  • Medication was protected from light
  • Procedure A: 30 days at 50 degrees C and 100% relative humidity
  • Procedure B: 30 days at 50 degrees C and 100% relative humidity followed by 5 days at 70 degrees C and 100% relative humidity
Temperature (degrees Celsius)
50, 70
Humidity (%)
100
Countries Studied In
Not applicable (lab experiment)
Definition of Stability
  • A standard for a degraded sample was created that contained 10% degradation products and 90% of the label.
  • This standard was used to compare to the tested product during analytical testing.
Conclusions and Length of Stability

  • Procedure A: No degradation
  • Procedure B: 75% degradation compared to a reference standard

  • Author's conclusions: No decomposition is detected by thin-layer chromatography after procedure A, but after procedure B, the substance is completely degraded.

Reference
http://apps.who.int/medicinedocs/en/d/Jh1808e/


MeSH entry terms
  • Acetylsalicylic Acid
  • Acid, Acetylsalicylic
  • 2-(Acetyloxy)benzoic Acid
  • Acylpyrin
  • Aloxiprimum
  • Colfarit
  • Dispril
  • Easprin
  • Ecotrin
  • Endosprin
  • Magnecyl
  • Micristin
  • Polopirin
  • Polopiryna
  • Solprin
  • Solupsan
  • Zorprin
  • Acetysal
MeSH reference: http://www.ncbi.nlm.nih.gov/mesh/68001241
Written by: Alex Evans, PharmD
Reviewed by:Last updated: June 9, 2013